Author

Per-Eric Lund

Uppsala UniversityORCID 0000-0002-5994-5290Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:electrophysiology· 1 Organism:mouse· 1

Frequent Co-Authors

Muhmmad Omar‐HmeadiiD· 2 shared Sebastian BargiD· 2 shared Anders TengholmiD· 1 shared Anna Näätänen· 1 shared Anni I. NiemineniD· 1 shared Diego BalboaiD· 1 shared Eija JokitaloiD· 1 shared Emilia KuuluvaineniD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCell Biology

Muhmmad Omar‐HmeadiORCID

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2 papers

Recent·Most cited

Pancreatic δ-cells are resistant to auto- and paracrine inhibition in human type-2 diabetes

Muhmmad Omar‐Hmeadi, Lina Matuseviciene, Liangwen Liu, Per-Eric Lund, Sebastian Barg

The paper investigates δ-cell function in type-2 diabetes, finding that these cells become resistant to inhibition, leading to hyperactivity and impaired glucose control.

Proceedings of the National Academy of Sciences · Oct 27, 2026Peer-reviewedCell Biology

Functional, metabolic and transcriptional maturation of stem cell derived beta cells

Diego Balboa, Tom Barsby, Väinö Lithovius, Jonna Saarimäki‐Vire, Muhmmad Omar‐Hmeadi, Oleg Dyachok, Hossam Montaser, Per-Eric Lund, Mingyu Yang, Hazem Ibrahim, Anna Näätänen, Vikash Chandra, Helena Vihinen, Eija Jokitalo, Jouni Kvist, , Timo Otonkoski

This study generates and benchmarks functionally mature stem cell-derived islets, showing they closely resemble primary adult islets in transcriptional and functional properties.

Nature Biotechnology · Mar 3, 2022Peer-reviewedDevelopmental Biology