Author

Guillem Montamat

The Royal Free HospitalORCID 0000-0003-2922-7092Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Claudia MauriiD· 4 shared Christopher J. M. PiperiD· 2 shared Deborah K. Dunn‐WaltersiD· 2 shared Franca FraternaliiD· 2 shared Joseph Chi-Fung NgiD· 2 shared Paul A. BlairiD· 2 shared Zara BaigiD· 2 shared Alan David SalamaiD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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4 shared papersImmunology

Claudia MauriORCID

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4 papers

Recent·Most cited

ImmunologybioRxivPreprintJun 29, 2026

B-cell SIGLEC-5 engages T-cell components of the elastin receptor complex (ERC) to suppress inflammatory T-cell cytokines

Christopher J. M. Piper, Clive Metcalfe, Maana Layeghi…·Claudia Mauri

The paper identifies SIGLEC-5 as an inhibitory receptor on B-cells that suppresses T-cell inflammatory cytokines by engaging the elastin receptor complex.

DOI 10.64898/2026.06.24.734204

humanexperimental assay

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ImmunologybioRxivPreprintFeb 6, 2026

Neutrophils impair B cell differentiation via mitochondrial and lipid metabolism in lupus.

Hannah F. Bradford, Guillem Montamat, Leire Goicoechea Barrenechea…·Marilina Antonelou

This study shows neutrophil-derived mitochondrial DNA impairs B cell differentiation in lupus nephritis through oxidative stress and lipid metabolism disruption.

DOI 10.64898/2026.02.03.703615

humanbulk RNA-seq

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ImmunologybioRxivPreprintMay 7, 2025

Multi-step antibody class switching in a primary human response is restricted after IGHG2 and dependent on B cell maturation stage.

Guillem Montamat, Joseph Chi-Fung Ng, Alex Stewart…·Deborah K. Dunn‐Walters

The paper investigates antibody class switching dynamics in a primary human immune response, revealing multistep progression and memory B cell subtype dependence beyond IGHG2.

DOI 10.1101/2025.05.07.652638

humanbulk RNA-seq

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BioinformaticsNature MethodsPeer-reviewedNov 6, 2023

sciCSR infers B cell state transition and predicts class-switch recombination dynamics using single-cell transcriptomic data

Joseph Chi-Fung Ng, Guillem Montamat, Alexander T. Stewart…·Franca Fraternali

22 citations

mousescRNA-seq

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