Author

Parnika S. Kadam

University of PennsylvaniaORCID 0000-0003-2924-217XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:ATAC-seq· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

David IssadoreiD· 2 shared James H. EberwineiD· 2 shared Yasemin Atiyas· 2 shared Andrew TsourkasiD· 1 shared Bonirath ChhayiD· 1 shared Erik C. NordgreniD· 1 shared Hua Zhu· 1 shared Juhwan ParkiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersNeuroscience

David IssadoreORCID

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2 papers

Recent·Most cited

NeuroscienceBMC BiologyPeer-reviewedJul 29, 2024

Single-Mitochondrion Sequencing Uncovers Distinct Mutational Patterns and Heteroplasmy Landscape in Mouse Astrocytes and Neurons.

Parnika S. Kadam, Zijian Yang, Youtao Lu…·James H. Eberwine

The paper analyzes mtDNA SNVs in single mitochondria from mouse neurons and astrocytes, revealing cell-type-specific mutation patterns and purifying selection.

5 citations

mouseATAC-seq

𝕏 PostBluesky

BioengineeringAngewandte Chemie International EditionPeer-reviewedMar 12, 2024

High-throughput single-cell, single-mitochondrial DNA assay using hydrogel droplet microfluidics

Juhwan Park, Parnika S. Kadam, Yasemin Atiyas…·David Issadore

This paper introduces a high-throughput method for single-cell, single-mtDNA analysis using agarose-based droplet microfluidics, achieving high mtDNA retention and enabling scalable analysis.

15 citations

ATAC-seqscRNA-seq

𝕏 PostBluesky