Author

Sarah A. B. Winchester

Gladstone InstitutesORCID 0000-0003-2924-4757Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Benoit G. BruneauiD· 2 shared Deepak SrivastavaiD· 2 shared Martin H. DomingueziD· 2 shared Reuben ThomasiD· 2 shared Alexis Leigh KrupiD· 1 shared André ForjaziD· 1 shared Andrew J. ConnollyiD· 1 shared Arun PadmanabhaniD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersDevelopmental Biology

Benoit G. BruneauORCID

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3 papers

Recent·Most cited

Developmental BiologyNature Cardiovascular ResearchPeer-reviewedDec 29, 2025

A disrupted compartment boundary underlies abnormal cardiac patterning and congenital heart defects

Irfan S. Kathiriya, Martin H. Dominguez, Kavitha S. Rao…·Benoit G. Bruneau

The paper identifies Tbx5 as a gene critical for forming a compartment boundary in the interventricular septum, and shows its disruption leads to congenital heart defects.

9 citations

mouseexperimental assay

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Developmental BiologyDevelopmentPeer-reviewedMar 30, 2023

A Mesp1-dependent developmental breakpoint in transcriptional and epigenomic specification of early cardiac precursors

Alexis Leigh Krup, Sarah A. B. Winchester, Sanjeev S. Ranade…·Benoit G. Bruneau

The paper identifies a Mesp1-dependent developmental breakpoint in cardiac precursor cell specification using single-cell transcriptomics and chromatin accessibility analysis in mouse embryos.

18 citations

mousescRNA-seq

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Molecular BiologyCirculationPeer-reviewedOct 23, 2020

BRD4 Interacts with GATA4 to Govern Mitochondrial Homeostasis in Adult Cardiomyocytes

Arun Padmanabhan, Michael Alexanian, Ricardo Linares-Saldana…·Deepak Srivastava

This study identifies a BRD4-GATA4 interaction that regulates mitochondrial homeostasis in adult cardiomyocytes by modulating gene expression related to energy production.

60 citations

mousebulk RNA-seq

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