Martin H. Dominguez

This study shows that dynamin 2 is essential for neural stem cell maintenance through its role in endocytosis, which differentially regulates Notch ligand and receptor activity.

The paper identifies Tbx5 as a gene critical for forming a compartment boundary in the interventricular septum, and shows its disruption leads to congenital heart defects.

This study shows that YAP/TAZ signaling in allantois-derived cells is essential for placental vascularization, as its loss causes embryonic lethality and vascular defects.

The paper identifies a Mesp1-dependent developmental breakpoint in cardiac precursor cell specification using single-cell transcriptomics and chromatin accessibility analysis in mouse embryos.

This study uses live embryo imaging to show how mesoderm gradients guide heart development through spatial and temporal morphodynamics.