Author

Alexis Leigh Krup

Gladstone InstitutesORCID 0000-0001-5555-0155Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1

Frequent Co-Authors

Benoit G. BruneauiD· 2 shared Martin H. DomingueziD· 2 shared Ayushi AgrawaliD· 1 shared Brian L. BlackiD· 1 shared Chang XieiD· 1 shared Deepak SrivastavaiD· 1 shared Jeremy F. ReiteriD· 1 shared Jonathon M. MuncieiD· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersDevelopmental Biology

Benoit G. BruneauORCID

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3 papers

Recent·Most cited

Developmental BiologyDevelopmentPeer-reviewedMar 30, 2023

A Mesp1-dependent developmental breakpoint in transcriptional and epigenomic specification of early cardiac precursors

Alexis Leigh Krup, Sarah A. B. Winchester, Sanjeev S. Ranade…·Benoit G. Bruneau

The paper identifies a Mesp1-dependent developmental breakpoint in cardiac precursor cell specification using single-cell transcriptomics and chromatin accessibility analysis in mouse embryos.

18 citations

mousescRNA-seq

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Developmental BiologybioRxivPreprintAug 1, 2022

A spatiotemporal gradient of mesoderm assembly governs cell fate and morphogenesis of the early mammalian heart

Martin H. Dominguez, Alexis Leigh Krup, Jonathon M. Muncie, Benoit G. Bruneau

This study uses live embryo imaging to show how mesoderm gradients guide heart development through spatial and temporal morphodynamics.

3 citations

mousespatial transcriptomics

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Developmental BiologybioRxivPreprintAug 31, 2020

Ciliary signaling-patterned smooth muscle drives tubular elongation

Yang Ying, Pekka Päivinen, Chang Xie…·Jeremy F. Reiter

This study shows that ciliary signaling patterns smooth muscle, which generates mechanical forces that activate YAP to drive longitudinal growth in the developing esophagus and small intestine.

2 citations

mousebulk RNA-seq

𝕏 PostBluesky