Author

Timothy E. Vanderleest

Massachusetts Eye and Ear InfirmaryORCID 0000-0003-2929-5378Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Ana Y. BaenaiD· 1 shared David Fernando AguilloniD· 1 shared Diego Sepúlveda FallaiD· 1 shared FJ Lopera· 1 shared Guido N. VacanoiD· 1 shared Joseph F. Arboleda‐VelásqueziD· 1 shared Justin S. SancheziD· 1 shared MA Mendivil-Perez· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Ana Y. BaenaORCID

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1 paper

Recent·Most cited

NeurosciencebioRxivPreprintJan 11, 2023

APOE3 Christchurch modulates tau phosphorylation and regulates β-catenin/Wnt/Cadherin signaling in induced pluripotent stem cell-derived cerebral organoids from Alzheimer's cases

Randall C. Mazzarino, Paula Andrea Perez-Corredor, Timothy E. Vanderleest…·Joseph F. Arboleda‐Velásquez

This study shows that the APOE3Ch variant reduces tau phosphorylation and regulates Wnt/Cadherin signaling in cerebral organoids from Alzheimer's cases, suggesting a protective mechanism against tauopathy.

7 citations

humanexperimental assay

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