Pharmacology & ToxicologybioRxivPreprint
Correlative evaluation of anticancer effects of a modified methioninase MGL-KPV using 2D and 3D cell models, human cancer xenografts in zebrafish embryos and Balb/c nude mice
Irina I. Khan, Saida Sh. Karshieva, Darina V. Sokolova…·Vadim S. Pokrovsky
This study evaluates the anticancer effects of MGL-KPV across 2D/3D cell models, zebrafish xenografts, and mice, showing significant tumor reduction and selective cytotoxicity.