Synthetic BiologyACS Synthetic BiologyPeer-reviewed
Sense-and-respond payload delivery using a novel antigen-inducible promoter improves suboptimal CAR-T activation
Tingxi Guo, Dacheng Ma, Timothy K. Lu
This paper introduces a novel antigen-inducible promoter to enhance CAR-T cell activation in low-immunogenic environments, showing improved cytokine expression and T cell proliferation.