Author

Sebastian Coupe

Massachusetts Institute of TechnologyORCID 0000-0003-3033-3562Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Assay:protein sequence· 1 Assay:proteomics· 1

Frequent Co-Authors

Nikta FakhriiD· 2 shared Ankur JainiD· 1 shared Sumit Majumder· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

3 top collaborators · 3 mutual co-author links

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2 shared papersBiophysics

Nikta FakhriORCID

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2 papers

Recent·Most cited

BiophysicsSoft MatterPeer-reviewedJan 1, 2026

Nonequilibrium phases of a biomolecular condensate facilitated by enzyme activity

Sebastian Coupe, Nikta Fakhri

The paper investigates how DEAD-box helicase activity influences the dynamic behavior of RNA-based biomolecular condensates through nonequilibrium mechanisms.

3 citations

protein sequenceproteomics

𝕏 PostBluesky

BiophysicsNature CommunicationsPeer-reviewedMay 7, 2025

Sequence programmable nucleic acid coacervates

Sumit Majumder, Sebastian Coupe, Nikta Fakhri, Ankur Jain

This study creates programmable DNA and RNA liquids that can be tuned by sequence-specific hybridization to control their material properties.

29 citationstop 2%

DNA methylationexperimental assay

𝕏 PostBluesky