Cancer BiologybioRxivPreprint
C. elegans models of Marfan and Marfan-like Syndromes reveal trafficking defects of the type II TGFβ receptor as a potential novel disease mechanism
Jing Lin, Mehul Vora, Nanci S. Kane…·Richard W. Padgett
This paper investigates Marfan and Marfan-like syndromes in C. elegans, revealing that type II TGFβ receptor mutations cause mis-trafficking rather than loss of function, suggesting a novel disease mechanism.
DOI 10.1101/486381