Chao Wang

This study uses multiscale multimodal data integration in a mouse model of traumatic brain injury to identify biomarkers of memory deficits and network dedifferentiation.

This study identifies sex-divergent type 1, 2, and 17 cytokine responses in brain-resident lymphocytes under chronic stress, revealing sex-specific regulatory mechanisms.

This study shows that ODC1 suppresses age-associated B cell features in meningeal inflammation of MS and EAE, affecting disease severity.

This study uses single-cell RNA sequencing to identify immune changes in the colon of Alzheimer's disease mice, finding reduced antibody-secreting cells and altered immune trafficking.

This study shows that cigarette smoke exposure promotes a pro-inflammatory lung environment that enhances the activation of myelin-reactive T helper cells, contributing to autoimmune disease.

The paper introduces Compass, an algorithm that uses single-cell RNA-Seq and flux balance analysis to characterize metabolic states in Th17 cells, revealing a metabolic switch and novel anti-inflammatory regulators.