A Compound Enhancing Lysosomal Function Reduces Tau Pathology, Microglial Reactivity and Rescues Working Memory in 3xTg AD Mice
Zachary Mayeri, Georgia Woods, Anand Rane, A Kifle, Manish Chamoli, Shikha Shukla, Chaska C. Walton, Julie Kay Andersen
This study evaluates a natural compound (MIC) that reduces tau pathology and microglial reactivity in 3xTgAD mice and rescues working memory, suggesting it as a potential therapeutic for Alzheimer's disease.
GeroScience · Mar 6, 2026Peer-reviewedNeuroscience