Author

Yuyu Zhang

Fudan UniversityORCID 0000-0003-3095-3083Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Immunology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Ben J. BrintziD· 1 shared Caiyun WangiD· 1 shared Chenglin ChiiD· 1 shared Chenxi XiaoiD· 1 shared Chris StubbeniD· 1 shared Christos P. KyriakopoulosiD· 1 shared Craig H. SelzmaniD· 1 shared Eleni TseliouiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperBioinformatics

Ben J. BrintzORCID

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3 papers

Recent·Most cited

BioinformaticsbioRxivPreprintApr 26, 2026

Integrative Clinical-Molecular Modeling Identifies LRRN4CL as a Determinant of Structural and Functional Myocardial Improvement

Ezra Johnson, Joseph R. Visker, Ben J. Brintz…·Stavros George Drakos

This paper integrates clinical and transcriptomic data to identify LRRN4CL as a predictor of myocardial recovery in heart failure patients undergoing LVAD therapy, showing its association with cardiomyocyte dysfunction.

DOI 10.64898/2026.04.21.720029

humanbulk RNA-seq

𝕏 PostBluesky

ImmunologyVirulencePeer-reviewedAug 21, 2025

PRRSV evades innate immune cGAS-STING antiviral function via its Nsp5 to deter STING translocation and activation

Yulin Xu, Chenglin Chi, Qihang Xin…·Jianzhong Zhu

This study identifies PRRSV's Nsp5 protein as a mechanism to inhibit the cGAS-STING-IFN antiviral pathway by blocking STING translocation and activation, thereby promoting viral replication.

10 citations

experimental assayhost-pathogen & immune response

𝕏 PostBluesky

Molecular BiologybioRxivPreprintJul 29, 2024

Deletion of Setd7 protects against cardiac hypertrophy via inhibiting lipid oxidation

Haibi Su, Jinghuan Wang, Yuyu Zhang…·Xinhua Liu

This study shows that deleting Setd7 reduces cardiac hypertrophy by inhibiting lipid oxidation through the Setd7-E2F1-WWP2-GPx4 pathway.

DOI 10.1101/2024.07.29.605718

mousestatistical model

𝕏 PostBluesky