Author

James R. Zengel

Stanford MedicineORCID 0000-0003-3153-3603Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Assay:scRNA-seq· 2 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Approach:deep learning· 1

Frequent Co-Authors

Jan E. CaretteiD· 3 shared Arjun RustagiiD· 2 shared Catherine A. BlishiD· 2 shared Aaron J. WilkiD· 1 shared Adam BegemaniD· 1 shared Aditya R. JangidiD· 1 shared Aimee BeckiD· 1 shared Alessandra Livraghi-ButricoiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersMicrobiology

Jan E. CaretteORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

MicrobiologybioRxivPreprintJul 15, 2025

Dissecting the host determinants of flavivirus infection using QIC-seq

Allison Dupzyk, Benjamin S. Waldman, James R. Zengel, Jan E. Carette

This study uses QIC-seq to compare host factor requirements and transcriptional responses to flavivirus infections, revealing differences in dependency on cellular pathways.

1 citation

humanscRNA-seq

𝕏 PostBluesky

GeneticsNature GeneticsPeer-reviewedJul 25, 2022

Genome-wide, bidirectional CRISPR screens identify mucins as critical host factors modulating SARS-CoV-2 infection

Scott B. Biering, Sylvia A. Sarnik, Eleanor Wang…·Patrick D. Hsu

The paper uses CRISPR screens to identify mucins as key host factors that restrict SARS-CoV-2 infection in human lung cells.

142 citationstop 1%

humanCRISPR screen

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GenomicsbioRxivPreprintJul 1, 2021

CRISPRa screening with real world evidence identifies potassium channels as neuronal entry factors and druggable targets for SARS-CoV-2

Chengkun Wang, Ravi K. Dinesh, Yuanhao Qu…·Le Cong

The paper uses CRISPRa screening and real-world data to identify KCNA6 as a neuronal entry factor for SARS-CoV-2 and shows dalfampridine can suppress viral entry.

7 citations

humanscRNA-seq

𝕏 PostBluesky