Author

Jonathan E. Farley

Alnylam Pharmaceuticals (United States)ORCID 0000-0003-3163-5570Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:non-human primate· 1 Approach:statistical model· 1

Frequent Co-Authors

Adam B. Castoreno· 1 shared Alissa A. CoffeyiD· 1 shared Andreja AvberšekiD· 1 shared Carlos E. Pedraza· 1 shared Carlos Umaña· 1 shared Carrie Garron· 1 shared Christos A. KyratsousiD· 1 shared Daniel A. SpragueiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperNeuroscience

Adam B. Castoreno

Mutual co-authors in cluster

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintOct 24, 2026

Prevention of prion disease symptoms in mice with deep PrP lowering

Juliana E Gentile, Jonathan E. Farley, Margaret N. Kelemen…·Eric Vallabh Minikel

This study demonstrates that deep PrP lowering with a potent siRNA prevents prion disease symptoms in mice and extends survival in symptomatic animals.

DOI 10.64898/2026.10.22.761034

mousehuman

𝕏 PostBluesky

NeurosciencebioRxivPreprintJul 8, 2025

GPR17 modulates oligodendrocyte precursor cell maturation during development but has limited impact on myelin regeneration following demyelinating insults

Kristin Puorro-Radzwill, Petti T. Pang, Stefanie Giera…·Carlos E. Pedraza

This study investigates GPR17's role in oligodendrocyte precursor cell maturation and myelin regeneration, finding limited impact on myelin repair after injury.

DOI 10.1101/2025.07.08.659146

mousestatistical model

𝕏 PostBluesky