Author

Wim Thiels

KU LeuvenORCID 0000-0003-3183-6209Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 3 Assay:imaging· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:dimensionality reduction· 1

Frequent Co-Authors

Casper van BaveliD· 3 shared Rob JelieriD· 3 shared Jef VangheeliD· 2 shared Michiel VanslambrouckiD· 2 shared Bart SmeetsiD· 1 shared Bart SmeetsiD· 1 shared Keyu Xiao· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 19 mutual co-author links

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3 shared papersBioinformatics

Casper van BavelORCID

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3 papers

Recent·Most cited

Developmental BiologybioRxivPreprintApr 1, 2026

Integrated quantitative imaging and biomechanical modeling of early gastrulation in C. elegans

Wim Thiels, Michiel Vanslambrouck, Casper van Bavel…·Rob Jelier

The paper integrates biomechanical modeling with imaging data to analyze the mechanics of cell ingression during C. elegans gastrulation, showing apical constriction and coordinated cell divisions drive the process.

DOI 10.64898/2026.03.30.715391

C. elegansimaging

𝕏 PostBluesky

BioinformaticsPLoS Computational BiologyPeer-reviewedDec 2, 2024

Image-based force inference by biomechanical simulation

Michiel Vanslambrouck, Wim Thiels, Jef Vangheel…·Rob Jelier

The paper introduces a method to infer forces from microscopy images of C. elegans embryos, validated by laser ablation, to study morphogenesis.

8 citations

C. elegansimaging

𝕏 PostBluesky

BioinformaticsBioinformaticsPeer-reviewedJun 1, 2023

Cell shape characterization, alignment and comparison using FlowShape

Casper van Bavel, Wim Thiels, Rob Jelier

The paper introduces FlowShape, a framework for analyzing cell shapes using spherical harmonics decomposition, and applies it to study shape changes in C. elegans embryos.

8 citations

C. elegansimaging

𝕏 PostBluesky