Ke Liu

This study evaluates cell lines as models for metastatic prostate cancer using multi-omics data, revealing genomic differences and identifying cell lines that better resemble metastatic samples.

CFMF identifies marker genes without clustering, showing improved sensitivity for rare cells and uncovering novel markers in multiple scRNA-seq datasets.

The paper analyzes CTGs across cancers using single-cell and spatial transcriptomics to identify regulatory patterns and therapeutic targets.

The paper investigates neomycin's binding to human ribosomes using Cryo-EM and functional assays, revealing structural binding patterns that differ from cellular observations.

The paper introduces UBS93, a computational framework for single-cell molecular subtyping, revealing coexistence of Basal-like and Claudin-low subtypes in human Basal-like breast cancer.

The paper identifies common mechanisms of action among anti-SARS-CoV-2 drugs and shows that targeting cholesterol homeostasis and microtubule cytoskeleton organization synergizes with antivirals.

This study evaluates the genomic similarity between breast cancer cell lines and metastatic samples, finding significant differences and highlighting organoids as better models.