Molecular BiologybioRxivPreprint
Identification of in vivo CFTR conformations during biogenesis and upon misfolding by covalent protein painting (CPP)
Sandra Pankow, Casimir Bamberger, Salvador Martínez‐Bartolomé…·John R. Yates
This study uses CPP to identify CFTR conformational changes during biogenesis and misfolding, revealing a novel opening mechanism and highlighting the role of the ICL2:NBD2 interface.
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