Casimir Bamberger

The paper uses in vivo protein footprinting to study dynamic conformational changes in the proteome across multiple tissues in Alzheimer's disease progression, finding that structural changes precede expression changes in key pathways.

This study uses CPP to identify CFTR conformational changes during biogenesis and misfolding, revealing a novel opening mechanism and highlighting the role of the ICL2:NBD2 interface.

This study identifies host proteins interacting with SARS-CoV-2 spike protein, showing that D614G mutation affects spike processing and tropism, and introduces pCtSEA to analyze cell type-specific interactions.

This study uses proteomic techniques to profile newly synthesized proteins in AD transgenic mice, revealing age-dependent changes and dysregulated vesicle transport networks prior to Aβ accumulation.