Salvador Martínez‐Bartolomé

This study identifies key structural and glycosylation features of EtpA, an ETEC adhesin, and shows how antibodies target different epitopes to influence immune responses and pathogen-host interactions.

This study uses CPP to identify CFTR conformational changes during biogenesis and misfolding, revealing a novel opening mechanism and highlighting the role of the ICL2:NBD2 interface.

This study identifies host proteins interacting with SARS-CoV-2 spike protein, showing that D614G mutation affects spike processing and tropism, and introduces pCtSEA to analyze cell type-specific interactions.

This study uses proteomic techniques to profile newly synthesized proteins in AD transgenic mice, revealing age-dependent changes and dysregulated vesicle transport networks prior to Aβ accumulation.

TargetSeeker-MS identifies drug targets on a proteome scale using EBPS-MS data, showing reproducibility in C. elegans and HEK293 samples treated with benomyl.

The paper identifies proteome-wide changes in mouse models of Alzheimer's disease, highlighting ApoE dysregulation and synaptic protein loss.