Alan Y. Du

The paper analyzes the contribution of transposable elements to regulatory elements in the human genome using ENCODE data, finding that ~25% of cCREs are TE-derived and show regulatory features similar to non-TE cCREs.

The paper introduces a comparative epigenome browser that enables visualization and comparison of genomic and epigenomic data across species and genome assemblies.

The paper tests the regulatory activity of human LTR18A transposable elements and finds they have lost activity over time due to mutations in AP-1 and C/EBP motifs.