Author

Jason D. Chobirko

Cornell UniversityORCID 0000-0001-8495-9152Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Assay:ChIP-seq· 2 Assay:DNA methylation· 2 Approach:experimental assay· 2

Frequent Co-Authors

Andrew GrimsoniD· 2 shared Cedric FeschotteiD· 2 shared Adrian J. McNairniD· 1 shared Alan Y. DuiD· 1 shared Brian D. RuddiD· 1 shared Cybelle TabilasiD· 1 shared Elizabeth A. FogartyiD· 1 shared Hongya ZhuiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersGenomics

Andrew GrimsonORCID

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3 papers

Recent·Most cited

Pervasive cis-regulatory co-option of a transposable element family reinforces cell identity across the mouse immune system

Jason D. Chobirko, Cedric Feschotte, Andrew Grimson

The paper identifies two rodent-specific transposable element subfamilies that function as cell-type-specific enhancers in the mouse immune system, contributing to cell identity and gene regulation.

The EMBO Journal · Oct 28, 2026Peer-reviewedGenomics

Deciphering gene regulatory programs underlying functionally divergent naive T cell subsets

Hongya Zhu, Ya Jiang, Adrian J. McNairn, Elizabeth A. Fogarty, Cybelle Tabilas, Ravi K. Patel, Jason D. Chobirko, Paul R. Munn, Norah L. Smith, Jennifer K. Grenier, Brian D. Rudd, Andrew Grimson

The paper identifies gene regulatory programs distinguishing naive CD8+ T cell subsets using RNA-seq and ATAC-seq data, revealing novel regulators and transcriptional networks.

bioRxiv · Nov 6, 2024 · PreprintSystems Biology

Regulatory Transposable Elements in the Encyclopedia of DNA Elements

Alan Y. Du, Jason D. Chobirko, Xiaoyu Zhuo, Cédric Feschotte, Ting Wang

The paper analyzes the contribution of transposable elements to regulatory elements in the human genome using ENCODE data, finding that ~25% of cCREs are TE-derived and show regulatory features similar to non-TE cCREs.

Nature Communications · Aug 31, 2024Peer-reviewedGenomics