Author

Celeste Giansanti

Vanderbilt UniversityORCID 0000-0003-3229-8385Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:DNA methylation· 1 Organism:human· 1

Frequent Co-Authors

David CorteziD· 2 shared Alessandro VindigniiD· 1 shared Brandt F. EichmaniD· 1 shared Courtney A. LovejoyiD· 1 shared Jack C. SchultziD· 1 shared Jessica Rose JacksoniD· 1 shared Jorge Rua-Fernandez· 1 shared Katherine A. PauliniD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMolecular Biology

David CortezORCID

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2 papers

Recent·Most cited

Molecular BiologyNature CommunicationsPeer-reviewedJun 30, 2026

FET proteins and PARylation-dependent condensates promote replication fork reversal and genome stability

Celeste Giansanti, Jack C. Schultz, Jessica Rose Jackson…·David Cortez

This study investigates how FET proteins and PARylation affect replication fork dynamics and genome stability upon PARG inhibition.

DOI 10.1038/s41467-026-74950-9

humanexperimental assay

𝕏 PostBluesky

Molecular BiologyCell ReportsPeer-reviewedNov 1, 2023

Self-reversal facilitates the resolution of HMCES-DNA protein crosslinks in cells

Jorge Rua-Fernandez, Courtney A. Lovejoy, Kavi P.M. Mehta…·David Cortez

The paper shows that HMCES-DNA protein crosslinks are resolved through self-reversal, which is crucial for managing ssDNA abasic sites and maintaining genome stability.

23 citations

DNA methylationexperimental assay

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