Author

Alexander J. Metcalf

Colorado School of MinesORCID 0000-0003-3247-4465Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:metabolomics· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Nanette R. BoyleiD· 2 shared Cara L. SakeiD· 1 shared Jorge Di PaolaiD· 1 shared Keith B. NeevesiD· 1 shared Michelle MeagheriD· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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2 shared papersSystems Biology

Nanette R. BoyleORCID

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2 papers

Recent·Most cited

Systems BiologybioRxivPreprintJan 24, 2022

Rhythm of The Night (and Day): Predictive metabolic modeling of circadian growth in Chlamydomonas

Alexander J. Metcalf, Nanette R. Boyle

The paper develops a transient metabolic model for diurnal growth of Chlamydomonas using transcriptomic data, predicting phenotypes from genotypes under dynamic conditions.

1 citation

C. elegansbulk RNA-seq

𝕏 PostBluesky

Systems BiologyMetabolic EngineeringPeer-reviewedDec 22, 2021

Isotopically Nonstationary 13C Metabolic Flux Analysis in Resting and Activated Human Platelets

Cara L. Sake, Alexander J. Metcalf, Michelle Meagher…·Nanette R. Boyle

This study uses isotopically nonstationary 13C metabolic flux analysis to measure carbon fluxes in resting and thrombin-activated human platelets, revealing metabolic shifts during activation.

22 citations

humanmetabolomics

𝕏 PostBluesky