Ying Shan

This study uses snRNA-seq to show that 17-estradiol treatment in aged rats reduces aging-related neuronal stress and alters HPG axis activity and energy metabolism.

This paper introduces BayesRB, an extension of BayesR for dichotomous traits, showing improved SNP effect estimation and disease risk prediction compared to traditional methods.

This study identifies cholesterol levels and WBC counts as causal factors for COVID-19 severity through GWAS and MR analysis, and highlights type I interferon pathways in disease mechanisms.