Author

Ziyu Tao

Chinese Academy of SciencesORCID 0000-0003-3272-1227Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2 Bioinformatics· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 4 Assay:whole-genome sequencing· 4 Research Focus:variant calling· 3 Research Focus:benchmarking· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Tao WuiD· 4 shared Xuesong LiuiD· 4 shared Shixiang WangiD· 3 shared Chenxu WuiD· 2 shared Kaixuan DiaoiD· 2 shared Die Qiu· 1 shared Fuxiang CheniD· 1 shared Guangshuai WangiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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4 shared papersGenomics

Tao WuORCID

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4 papers

Recent·Most cited

GenomicsCommunications BiologyPeer-reviewedNov 17, 2025

Single-cell copy number alteration signature analysis reveals masked patterns and potential biomarkers for cancer

Chenxu Wu, Ziyu Tao, Wen Chen…·Xuesong Liu

This study analyzes CNA signatures in single-cell and bulk samples of hepatocellular carcinoma, revealing masked patterns and potential biomarkers for prognosis and treatment.

2 citations

humanwhole-genome sequencing

𝕏 PostBluesky

BioinformaticsBriefings in BioinformaticsPeer-reviewedJan 28, 2023

The repertoire of copy number alteration signatures in human cancer

Ziyu Tao, Shixiang Wang, Chenxu Wu…·Xuesong Liu

This study identifies 14 CNA signatures from pan-cancer WGS and TCGA SNP array data, revealing novel patterns and prognostic implications for cancer patients.

30 citationstop 5%

humanwhole-genome sequencing

𝕏 PostBluesky

Genetic & Genomic MedicinePLoS GeneticsPeer-reviewedMay 4, 2021

Copy number signature analyses in prostate cancer reveal distinct etiologies and clinical outcomes

Shixiang Wang, Huimin Li, Minfang Song…·Xuesong Liu

This study identifies five copy number signatures in prostate cancer using sigminer, revealing distinct etiologies and improved clinical outcome associations compared to single base substitution signatures.

143 citationstop 1%

humanwhole-genome sequencing

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GenomicsBioinformaticsPeer-reviewedOct 3, 2020

Sigflow: an automated and comprehensive pipeline for cancer genome mutational signature analysis

Shixiang Wang, Ziyu Tao, Tao Wu, Xuesong Liu

Sigflow is a pipeline for comprehensive cancer genome mutational signature analysis, supporting multiple DNA alteration types and offering reproducible research through Docker.

65 citationstop 4%

humanmouse

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