Author

Han-Wen Chang

Institute of Molecular Biology, Academia SinicaORCID 0000-0003-3275-7211Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Evolutionary Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Rebecca J. TayiD· 2 shared Yen‐Ping HsuehiD· 2 shared Ching-Ting Yang· 1 shared Dao-Ming Chang· 1 shared Hung‐Che LiniD· 1 shared Tzu-Hsiang LiniD· 1 shared Yi‐Chung TungiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 17 mutual co-author links

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2 shared papersEvolutionary Biology

Rebecca J. TayORCID

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2 papers

Recent·Most cited

Evolutionary BiologyPLoS BiologyPeer-reviewedJul 1, 2025

Cuticular collagens mediate cross-kingdom predator-prey interactions between nematodes and trapping fungi

Han-Wen Chang, Hung‐Che Lin, Ching-Ting Yang…·Yen‐Ping Hsueh

The paper identifies NHR-66 as a regulator of cuticular collagen genes in C. elegans that mediate adhesion to the nematode-trapping fungus Arthrobotrys oligospora, revealing a trade-off between predator resistance and physiological stress tolerance.

6 citations

C. elegansexperimental assay

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MicrobiologyiSciencePeer-reviewedMay 30, 2025

Predation by nematode-trapping fungus triggers mechanosensory-dependent quiescence in C. elegans

Tzu-Hsiang Lin, Han-Wen Chang, Rebecca J. Tay, Yen‐Ping Hsueh

This study shows that C. elegans becomes quiescent when trapped by the nematode-trapping fungus A. oligospora, involving mechanosensory neurons and immune gene upregulation.

7 citations

C. elegansbulk RNA-seq

𝕏 PostBluesky