BiophysicsJournal of the American Chemical SocietyPeer-reviewed
Glutamine Tautomerization Drives RhoGAP-Aided GTP Hydrolysis in Small Rho GTPases
Angela Parise, Riccardo Rozza, Karolina Mitusińska…·Alessandra Magistrato
The paper resolves the mechanism of GTP hydrolysis in the RhoGAP-RhoA complex, revealing a tautomerization-driven process involving Gln63.