BiochemistryProceedings of the National Academy of SciencesPeer-reviewed
Mitochondrial depolarization stabilizes the vitamin B12 chaperone MMADHC in the cytosol to increase MTR activity
Sneha P. Rath, Zhu Li, Arkajit Guha…·Vamsi Krishna Mootha
The paper identifies MMADHC as a mitochondrial protein that stabilizes in the cytosol upon PMF collapse, increasing MTR activity and one-carbon metabolism.
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