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A Multicenter Confirmatory Randomized-Controlled Study of rhNRGβ1 Protein Replacement Therapy in a Murine Model of NF2-related Schwannomatosis
Michael Reuter, Susann Groth, Johanna Schleep…·Helen Morrison
Across three German sites and 207 analyzed mice, systemic rhNRGβ1 at 10 µg/kg did not reduce schwannoma nerve thickness or shift Schwann cell differentiation markers.
DOI 10.64898/2026.07.31.741963