Helen Morrison

The paper evaluates multi-laboratory studies to identify promising treatments by assessing effect sizes and experimental rigor across different medical fields.

This study investigates sex-dependent proteomic changes in young and aged mouse peripheral nerves during ex vivo degeneration, revealing sex-specific molecular features of nerve ageing.

Across three German sites and 207 analyzed mice, systemic rhNRGβ1 at 10 µg/kg did not reduce schwannoma nerve thickness or shift Schwann cell differentiation markers.

This study identifies the TACR3 variant rs2765 as protective against age- and Alzheimer's-related cognitive decline, showing slower cognitive decline and younger epigenetic age in carriers.

This study compares molecular changes in PNS ageing, dietary restriction, and injury, finding similar proteomic signatures between ageing and injury.

The paper investigates how LPS preconditioning affects microglial proteome response to focal ischemic brain injury in mice, finding significant neuroprotection and changes in proteome patterns linked to type I interferons.

This study investigates changes in the myelin proteome of mouse peripheral nerves during aging, finding only subtle changes and proposing the dataset as a resource for future research.