David J. Klinke

This study shows that CCN4 promotes immunosuppression in breast cancer by altering the tumor microenvironment and immune cell composition.

This study compares the functional characteristics of two melanoma models, B16F0 and YUMM1.7, finding differences in tumor growth, chemosensitivity, and immunogenicity that suggest different applications for each model.

The paper uses Bayesian network inference and digital cytometry to model how oncogenic gene expression alters tumor microenvironments from bulk transcriptomic data.