Satyajit D. Rao

The paper demonstrates that mean and noise of gene expression can be independently controlled in E. coli by using two inducible promoters and shows how repressor noise affects promoter response.

The paper investigates stress-sensing mechanisms in Mycobacterium tuberculosis and M. smegmatis, showing hysteresis in pathogenic bacteria and revealing the role of DnaK in enabling fast and sustained responses.

This study uses mathematical modeling to investigate how positive and negative feedback loops in the PhoPQ two-component system influence its dynamical responses and steady-state behavior.