Maria Laura Gennaro

This study identifies PspA's role in maintaining membrane potential and supporting NADH dehydrogenase function in mycobacteria through interactions with PspM and menaquinone.

This paper shows that the mycobacterial ligand ManLAM uses structural features to engage TLR2 and Dectin-2, reprogramming macrophage lipid metabolism and promoting foam cell formation.

This study evaluates two compounds that reduce triglyceride content in Mtb-infected macrophages but finds they do not reduce bacterial burden or inflammation in infected mice.

The paper identifies novel partners and evolutionary history of phage shock protein (PSP) systems across bacteria, showing their presence in LUCA and diversification into new functional contexts.

The paper investigates stress-sensing mechanisms in Mycobacterium tuberculosis and M. smegmatis, showing hysteresis in pathogenic bacteria and revealing the role of DnaK in enabling fast and sustained responses.