Author
State Key Laboratory of Respiratory Disease
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
9 papers
Recent·Most cited
张则婷, Cai Zhang, Guohua Xu, Ruichen Du, Jinbo Yu, Xiaoli Liu, Zhaofei Chai, Qiong Wu, Ling Jiang, Maili Liu, Conggang Li
The paper uses high-resolution NMR spectroscopy to study protein interactions and modifications within intact mitochondria, providing insights into mitochondrial protein function and stability.
Nature Chemical Biology · Oct 7, 2026Peer-reviewedBiochemistry
Sunil Guharajan, Xiangyang Song, Sachi Sengupta, Qiong Wu, Wenyi Wei, Yan Xiong, Jian Jin, Sahin Naqvi
The paper introduces dubTAGs, small molecules that stabilize proteins tagged with FKBP12F36V by recruiting deubiquitinases, enabling tunable and reversible control of protein levels.
bioRxiv · Sep 18, 2026 · PreprintMolecular Biology
Qiong Wu, Xiangyang Song, Li Chen, Hroyuki Inuzuki, Janell Atkins, Yihang Qi, Yan Xiong, Wenyi Wei, Jian Jun Jin
The paper identifies a new four-membered-ring chemotype that selectively binds OTUB1, expands its ligandable chemical space, and enables the development of next-generation DUBTACs.
bioRxiv · Aug 27, 2026 · PreprintBiochemistry
Wenqi Li, Qiong Wu, Yongzhi Lu, Xiaoqin Li, Lei Miao, Xia Y, Xianjie Qiu, Miru Tang, Z Y Li, Yang Peng, Wenxiang Hu, Wei Kevin Zhang, Jie Zheng, Cong Ma, Jinsai Shang
This study identifies FXR as a suppressor of pulmonary fibrosis by interacting with PPP1CB to reduce SMAD2/3 phosphorylation, showing therapeutic potential with TERN101.
bioRxiv · Jul 24, 2026 · PreprintCell Biology
Kunzhong Wu, Qiong Wu, Yongzhi Lu, Qi Yang, Ting Ran, Jie Zhang, Xianjie Qiu, Chengjie Huang, Yue Lin, J K Chen, Z L Yang, Wei Qin, Zhu Liu, Xinqi Liu, Miru Tang, , Jinsai Shang
This paper introduces GZL626, a novel AR degrader that targets the N-terminal domain and RNF213-UBE2J2 complex, effectively degrading AR and AR-V7 and showing antitumor and antiviral activity.
bioRxiv · Jul 16, 2026 · PreprintBiophysics
Meng Lü, Wenkai Zhu, G Xu, J M Chen, Qiong Wu, Xiaoli Liu, Mingjuan Yang, Ling Jiang, Minghui Yang, Maili Liu, Conggang Li
This paper introduces two novel 19F NMR probes to study tyrosine ring-flip dynamics in proteins, showing they can quantify and modulate these motions in vitro and in living cells.
Analytical Chemistry · Jul 9, 2026Peer-reviewedBiochemistry
Jules Roger Dugre, Yidian Gao, Marlene Staginnus, Abigail A. Marsh, Alexandra Kypta-Vivanco, Ana Isabel Lafuente Cubillo, Andrea Dietrich, Anka Bernhard, Anne Martinelli, Anouk H. Dykstra, Areti Smaragdi, Arjun Sethi, Arun L.W. Bokde, Barbara Franke, Celso Arango, , Stéphane A. De Brito
This study investigates brain age differences in youth with conduct disorder compared to controls, finding accelerated brain maturation in those with adolescence-onset CD.
bioRxiv · Jan 21, 2026 · PreprintNeuroscience
Qiong Wu, Caixian Zhou, Yue Dou, Nadia I. Martin, Maria Gwit, Tae-Hee Lee, Mark Hedglin, Rosea Chen, Ke Zhu, Tianpeng Zhang, Shangming Tang, Tian Zhang, Tyler Weaver, Wenpeng Liu
This study shows that replication fork reversal is essential for maintaining epigenetic inheritance under replication stress by preventing nucleosome loss and ensuring histone transfer.
bioRxiv · Sep 21, 2025 · PreprintBiochemistry
Shuo Chen, Qiong Wu, L. Elliot Hong
The paper develops a graph combinatorics-based method for group-level network inference to identify phenotype-related brain subnetworks associated with schizophrenia.
bioRxiv · Dec 26, 2019 · PreprintNeuroscience