Author

Kamaldeep Aulakh

Hospital for Sick ChildrenORCID 0000-0003-3321-8041Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Adrian Granda FariasiD· 3 shared Andrea Habsid· 3 shared Jason MoffatiD· 3 shared Katherine ChaniD· 3 shared Kevin R. BrowniD· 3 shared Patricia Mero· 3 shared Amy H.Y. TongiD· 2 shared Brenda AndrewsiD· 2 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersSystems Biology

Adrian Granda FariasORCID

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3 papers

Recent·Most cited

Systems BiologybioRxivPreprintJun 30, 2025

A global genetic interaction map of a human cell reveals conserved principles of genetic networks

Maximilian Billmann, Michael Costanzo, Xiang Zhang…·Charles M. Boone

The paper constructs a genome-scale genetic interaction network from 4 million double mutants in HAP1 cells, revealing conserved genetic network principles across species and uncovering novel gene functions and cancer dependencies.

5 citations

humanexperimental assay

𝕏 PostBluesky

Cell BiologyCell ReportsPeer-reviewedJul 1, 2024

TSC22D, WNK and NRBP gene families exhibit functional buffering and evolved with Metazoa for macromolecular crowd sensing

Yu-Xi Xiao, Seon Yong Lee, Magali Aguilera-Uribe…·Jason Moffat

This study identifies functional relationships between TSC22D, WNK, and NRBP gene families in macromolecular crowding sensing and cell volume regulation across metazoans.

20 citations

multiple speciesgenetic perturbation / CRISPR

𝕏 PostBluesky

Systems BiologybioRxivPreprintJun 28, 2021

Systematic genome-scale identification of host factors for SARS-CoV-2 infection across models yields a core single gene dependency; ACE2

Katherine Chan, Adrian Granda Farias, Hunsang Lee…·Jason Moffat

The paper identifies ACE2 as the only common host dependency for SARS-CoV-2 across multiple cell lines, while other host factors are cell line specific.

1 citation

humanCRISPR screen

𝕏 PostBluesky