Shaunak Kar

ViralMap predicts ten annotation classes for viral proteins from primary sequences, achieving high performance on seven classes and generalizing across viral strains and families.

This study evolves a T7 RNA polymerase variant with a capping enzyme to enable efficient gene expression in eukaryotes, showing improved performance in yeast and mammalian cells.

This paper modifies a One Pot PURE system to enable modular incorporation of unnatural amino acids through orthogonal tRNA synthetases and stop codon suppression.

The paper designs synthetic promoters and CRISPR-based transcription factors to enable orthogonal gene expression control in plants, demonstrating a fully artificial Orthogonal Control System (OCS).