BioinformaticsbioRxivPreprint
Integrated ambient modeling and genetic demultiplexing of single-cell RNA+ATAC multiome experiments with Ambimux
Marcus Alvarez, Terence Li, Seung Hyuk Lee…·Päivi Pajukanta
The paper introduces ambimux, a method to estimate and demultiplex ambient molecule contamination in single-cell RNA+ATAC multiome data, improving the detection of biologically meaningful signals.