Author

Ru‐Ting Huang

University of ChicagoORCID 0000-0001-8360-9994Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Genetics· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:gene regulatory network inference· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1

Frequent Co-Authors

Yun Hua FangiD· 4 shared Jiayu ZhuiD· 3 shared Tzu‐Pin ShentuiD· 3 shared Casey E. RomanoskiiD· 2 shared Chih‐Fan YehiD· 2 shared David WuiD· 2 shared Devin L. HarrisoniD· 2 shared Jin Li· 2 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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4 shared papersMolecular Biology

Yun Hua FangORCID

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4 papers

Recent·Most cited

Molecular BiologyCirculationPeer-reviewedAug 11, 2026

Mechanosensitive Endothelial METTL7A Regulates Internal m7G mRNA Methylation and Protects Against Atherosclerosis

Tzu‐Pin Shentu, Tong Wu, Zhengjie Zhou…·Yun Hua Fang

This study identifies METTL7A as a mechanosensitive methyltransferase that regulates internal m7G methylation in endothelial cells, protecting against atherosclerosis through stabilization of anti-inflammatory transcripts.

4 citations

mousebulk RNA-seq

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BioengineeringbioRxivPreprintJan 9, 2025

Precision mRNA Nanomedicine for Targeted Vascular Therapies in ARDS and Atherosclerosis

Zhengjie Zhou, Jiayu Zhu, Chih‐Fan Yeh…·Yun Hua Fang

This paper develops a modular nanoparticle platform for targeted mRNA delivery to inflamed endothelial cells, showing efficacy in treating ARDS and atherosclerosis by restoring disease-related gene pathways.

6 citations

mousemultiome

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GeneticsArteriosclerosis Thrombosis and Vascular BiologyPeer-reviewedApr 11, 2024

Coronary Artery Disease risk variant dampens the expression of CALCRL by reducing HSF binding to shear stress responsive enhancer in endothelial cells

Ilakya Selvarajan, Miika Kiema, Ru‐Ting Huang…·Minna Unelma Kaikkonen

The paper identifies a CAD risk SNP rs880890 in an endothelial enhancer that reduces CALCRL expression by impairing HSF binding under shear stress.

6 citations

humanbulk RNA-seq

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GenomicsProceedings of the National Academy of SciencesPeer-reviewedNov 14, 2018

A genetic variant at coronary artery disease and ischemic stroke locus 1p32.2 regulates endothelial responses to hemodynamics

Matthew D. Krause, Ru‐Ting Huang, David Wu…·Yun Hua Fang

This study identifies a genetic variant at 1p32.2 that regulates endothelial responses to hemodynamics by modulating an enhancer region in vascular endothelium.

75 citationstop 5%

humanChIP-seq

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