Author

Shan Cen

Chinese Academy of Medical Sciences & Peking Union Medical CollegeORCID 0000-0003-3358-0411Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Hua CheniD· 1 shared Hui Bao· 1 shared Juan Li· 1 shared Kai LviD· 1 shared Lu Han· 1 shared Na LiiD· 1 shared Qiang LiiD· 1 shared Rui Qi· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBioengineering

Hua ChenORCID

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1 paper

Recent·Most cited

BioengineeringMolecular Therapy — Nucleic AcidsPeer-reviewedSep 8, 2026

Segmented poly(A) tails with microRNA target sites confer tissue-specific regulation for mRNA therapeutics

Rui Qi, Hua Chen, Hui Bao…·Weiguo Zhang

This study engineers segmented poly(A) tails with microRNA target sites to enable tissue-specific regulation of mRNA-LNPs, showing position-dependent expression control in vitro and in vivo.

DOI 10.1016/j.omtn.2026.103094

experimental assaydrug response / drug discovery

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