NeurosciencebioRxivPreprint
A focal traumatic injury to the spinal cord causes an immediate and massive spreading depolarization sustained by chloride ions, with transient network dysfunction and remote cortical glia changes.
Atiyeh Mohammadshirazi, Graciela L. Mazzone, Benjamín A. Zylberberg…·Giuliano Taccola
This study investigates the immediate effects of spinal cord injury in an in vitro model, revealing chloride ion-dependent depolarizations and transient cortical glial changes.