An electrophysiological study about the pharmacological manipulation of the immediate consequences of a spinal trauma reveals a crucial role for TRPV4 antagonism.
Atiyeh Mohammadshirazi, Giuliano Taccola
This study applies pharmacological agents immediately after spinal trauma in rats to identify treatments that reduce injury potentials and restore reflexes, finding TRPV4 antagonism and GABAA receptor modulation are effective.