Author

Christopher W. Cairo

University of AlbertaORCID 0000-0003-3363-8708Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Alexey V. PshezhetskyiD· 2 shared Xuefang PaniD· 2 shared Alexei GorelikiD· 1 shared Angelo PalmigianoiD· 1 shared Antoine CailloniD· 1 shared Aymeric FabiéiD· 1 shared Bénédicte AmilhoniD· 1 shared Bhushan NagariD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBiochemistry

Alexey V. PshezhetskyORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintSep 7, 2026

Inhibition of macrophage neuraminidase 1 protects against immune thrombocytopenia by limiting platelet clearance

Antoine Caillon, Lorena Carvelli, Xuefang Pan…·Alexey V. Pshezhetsky

This study shows that inhibiting macrophage NEU1 reduces platelet clearance in ITP by limiting phagocytosis, suggesting NEU1 as a therapeutic target.

DOI 10.64898/2026.09.03.748973

mouseexperimental assay

𝕏 PostBluesky

BiochemistryJournal of Clinical InvestigationPeer-reviewedJun 17, 2025

Secondary deficiency of neuraminidase 1 contributes to CNS pathology in neurological mucopolysaccharidoses via hypersialylation of brain glycoproteins

TianMeng Xu, Rachel Heon‐Roberts, Travis Moore…·Alexey V. Pshezhetsky

This study shows that reduced NEU1 activity in neurological MPS leads to hypersialylation of brain glycoproteins, contributing to CNS pathology through disrupted synaptogenesis and behavior.

5 citations

𝕏 PostBluesky