Author

Jessica Layne

Cold Spring Harbor LaboratoryORCID 0000-0003-3371-6796Unclaimed ORCID profile · follow to get notified of new preprints

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1

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Adrian R. KraineriD· 1 shared Dillon M. VossiD· 1 shared Lucia YangiD· 1 shared Nicole SivetziD· 1 shared Qian ZhangiD· 1 shared Young Jin KimiD· 1 shared

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2022-2022 · peak 1/yr

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1 shared paperMolecular Biology

Adrian R. KrainerORCID

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1 paper

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Molecular BiologyProceedings of the National Academy of SciencesPeer-reviewedJan 10, 2022

Exon-Skipping Antisense Oligonucleotides for Cystic Fibrosis Therapy

Young Jin Kim, Nicole Sivetz, Jessica Layne…·Adrian R. Krainer

This paper develops an exon-skipping antisense oligonucleotide (ASO) strategy to increase CFTR protein levels in patients with the W1282X mutation by bypassing nonsense-mediated mRNA decay.

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humanexperimental assay

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