Author

Young Jin Kim

Cold Spring Harbor LaboratoryORCID 0000-0003-1876-3359Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Adrian R. KraineriD· 2 shared Lucia YangiD· 2 shared Dillon M. VossiD· 1 shared Foteini PapaleonidopoulouiD· 1 shared Jessica LayneiD· 1 shared Nicole SivetziD· 1 shared Qian ZhangiD· 1 shared Qian ZhangiD· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 24 mutual co-author links

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2 shared papersMolecular Biology

Adrian R. KrainerORCID

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2 papers

Recent·Most cited

Molecular BiologyNature CommunicationsPeer-reviewedMay 27, 2022

Gene-Specific Nonsense-Mediated mRNA Decay Targeting for Cystic Fibrosis Therapy

Young Jin Kim, Tomoki T. Nomakuchi, Foteini Papaleonidopoulou…·Adrian R. Krainer

This study develops a cocktail of ASOs to specifically increase CFTR W1282X mRNA and protein levels by inhibiting NMD, improving chloride current in human bronchial epithelial cells.

41 citationstop 3%

humanexperimental assay

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Molecular BiologyProceedings of the National Academy of SciencesPeer-reviewedJan 10, 2022

Exon-Skipping Antisense Oligonucleotides for Cystic Fibrosis Therapy

Young Jin Kim, Nicole Sivetz, Jessica Layne…·Adrian R. Krainer

This paper develops an exon-skipping antisense oligonucleotide (ASO) strategy to increase CFTR protein levels in patients with the W1282X mutation by bypassing nonsense-mediated mRNA decay.

46 citationstop 2%

humanexperimental assay

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