Author

Qian Zhang

Cold Spring Harbor LaboratoryORCID 0000-0001-6721-3594Unclaimed ORCID profile · follow to get notified of new preprints

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Qian Zhang23 papers · Virginia Tech

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Adrian R. KraineriD· 2 shared Lucia YangiD· 2 shared Dillon M. VossiD· 1 shared Jessica LayneiD· 1 shared John Erby WilkinsoniD· 1 shared Nicole SivetziD· 1 shared Shivani DeshpandeiD· 1 shared Young Jin KimiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 20 mutual co-author links

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2 shared papersMolecular Biology

Adrian R. KrainerORCID

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2 papers

Recent·Most cited

Molecular BiologyMolecular Therapy — Nucleic AcidsPeer-reviewedJul 27, 2026

Exon-Skipping Antisense Oligonucleotides for H3.3K27M-Altered Diffuse Midline Glioma Therapy

Lucia Yang, Qian Zhang, John Erby Wilkinson…·Adrian R. Krainer

This study demonstrates that exon-skipping antisense oligonucleotides targeting H3.3K27M-altered DMG reduce proliferation and extend survival in a mouse model.

DOI 10.1016/j.omtn.2026.103040

mouseexperimental assay

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Molecular BiologyProceedings of the National Academy of SciencesPeer-reviewedJan 10, 2022

Exon-Skipping Antisense Oligonucleotides for Cystic Fibrosis Therapy

Young Jin Kim, Nicole Sivetz, Jessica Layne…·Adrian R. Krainer

This paper develops an exon-skipping antisense oligonucleotide (ASO) strategy to increase CFTR protein levels in patients with the W1282X mutation by bypassing nonsense-mediated mRNA decay.

46 citationstop 2%

humanexperimental assay

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