Bryan R. Helm

The paper creates a spatial atlas of early-stage colorectal cancer tumors to identify bacterial niches and their impact on tumor transcriptomes, highlighting C. difficile's significant influence despite low abundance.

The paper identifies seven thymic conventional dendritic cell subsets and their distinct functional roles and dependencies on thymocyte subsets for homeostasis and activation.

The paper examines molecular and cellular changes in thymic stromal and hematopoietic cells during the perinatal to juvenile transition in mice and humans, identifying key pathways and signaling changes.

The paper integrates mouse and human single-cell RNA sequencing data to predict and spatially map cell-type composition in human brain tissue.

BERMUDA corrects batch effects in scRNA-seq data and reveals hidden cellular subtypes by transferring information across batches.