Author

Kyle B. Lupo

Memorial Sloan Kettering Cancer CenterORCID 0000-0003-3442-0647Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:CITE-seq· 1

Frequent Co-Authors

Clara Lawry· 2 shared Gabryelle Kolk· 2 shared Katharine C. HsuiD· 2 shared Rosa SottileiD· 2 shared Ahmed Al‐NiaimiiD· 1 shared Anthony F. DaniyaniD· 1 shared Aya G. HalawiiD· 1 shared Brian C. ShafferiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersImmunology

Clara Lawry

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2 papers

Recent·Most cited

ImmunologyJournal of Clinical InvestigationPeer-reviewedOct 20, 2026

Engineered NKG2C+ NK-like T cells exhibit superior antitumor efficacy while mitigating cytokine release syndrome

Kyle B. Lupo, M. Kazim Panjwani, Aya G. Halawi…·Katharine C. Hsu

This study shows that engineered NKG2C+ NK-like T cells have better antitumor effects and lower cytokine release syndrome risk than conventional CAR-T and CAR-NK cells.

5 citations

humanCITE-seq

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ImmunologybioRxivPreprintJun 27, 2025

PD-L1 ligation on NK cells induces a metabolic shift from glycolysis to fatty acid oxidation, enhancing tumor infiltration and control

Katja Srpan, Kyle B. Lupo, Rosa Sottile…·Katharine C. Hsu

1 citation

humanproteomics

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