Styxl2 regulates de novo sarcomere assembly by binding to non-muscle myosin IIs and promoting their degradation
Xianwei Chen, Yanfeng Li, Jin Xu, Yong Cui, Qian Wu, Haidi Yin, Yuying Li, Chuan Gao, Liwen Jiang, Huating Wang, Zilong Wen, Zhong‐Ping Yao, Zhenguo Wu
This study identifies Styxl2 as a regulator of de novo sarcomere assembly by promoting degradation of non-muscle myosin IIs through autophagy.
eLife · May 5, 2023Peer-reviewedDevelopmental Biology